Accelerating the Proteomics Discovery to Quantification Pipeline
Date: Wednesday 6th October 2010
Time: 1pm EST / 10am PST
The need to identify and accurately quantify a protein or a panel of proteins in multiple samples is becoming increasingly important in the life sciences, pharmaceutical, clinical and food and beverage industries. But which protein to analyze may need a continuous research pipeline where key proteins in a biological system are discovered, and then verified and validated in greater numbers of samples to account for biological variation. Ultimately assays are developed for routine detection of the protein.
Discovery Proteomics using ‘shotgun’ mass spectrometry approaches generate many protein candidates but do not generally have the ability to quantitatively analyze large numbers of samples. Multiple reaction monitoring (MRM) mass spectrometry assays are relatively cheap and fast to develop, and the quantitative assays are reproducible and accurate. They can be performed in high throughput, and many proteins can be assayed in the same experiment.
This webinar highlights new technology for Discovery Proteomics, the TripleTOF™ 5600 System, and shows how the unique qualitative and quantitative capabilities accelerate the protein research pipeline. Dr. Mandy Paulovich will also present on coupling MRM technology to enrichment with anti-peptide antibodies to achieve highly precise, sensitive, multiplex
|
|
Dr. Mandy Paulovich (Associate Professor of the Fred Hutchinson Cancer Research Institute) |
Dr. Brigitte Simons (AB SCIEX, Applications Lab Manager) |
Dr. Amanda Paulovich earned her B.S. in Biology from Carnegie Mellon University in Pittsburgh, and her Ph.D. and M.D. degrees from the University of Washington in Seattle. She completed training in Internal Medicine at the Massachusetts General Hospital, and training in Medical Oncology at the Dana Farber Cancer Institute in Boston. In 2003, following postdoctoral studies in functional genomics at the Whitehead Institute in Boston, she returned to Seattle and established her own laboratory at the Fred Hutchinson Cancer Research Center. She is now an Associate Member and Director of the Early Detection Initiative at the Clinical Research Division at the FHCRC, and an adjunct Associate Professor in the Department of Medicine/Division of Oncology at the University Of Washington School Of Medicine. She runs a mass spectrometry-based laboratory focused on developing technologies for biomarker discovery and verification. Her laboratory has a particular focus on developing multiple reaction monitoring mass spectrometry coupled to stable isotope dilution and immunoaffinity enrichment for precise, multiplex quantitation of proteotypic peptides in complex matrices such as plasma.
Dr. Brigitte Simons is the proteomics application lead at AB SCIEX in Toronto. Prior to working at AB SCIEX, Brigitte received her Ph.D. in Chemical Biology at the University of Ottawa. She then completed two research fellowships at the Centre for Biologics Research at Health Canada and the National Institute of Heart Lung and Blood in Bethesda MD. Brigitte has published most recently in the field of phosphorylation-mediated cell signaling in application to kidney physiology jointly with collaborators from the National Institutes of Health.
http://mediazone.brighttalk.com/event/ReedElsevier/44b422a6d1-4212-intro
No. | 제목 | 작성자 | 첨 부 | 작성일 | 조회 |
---|---|---|---|---|---|
78 | [국립암센터] 2018년 기관고유연구사업 목적과제(암 단백유전체학 연구)… | admin | 2018.03.19 | 1797 | |
77 | MSP2018 (9th AOHUPO conference, 5/15-18,… | admin | 2018.02.28 | 2950 | |
76 | [YPRC]제42차 프로테오믹스 실험기술 워크숍 개최 (2018.2.22… | admin | 2018.01.08 | 2246 | |
75 | 2017년도 한국인체자원은행사업 심포지엄 개최 | admin | 2017.12.05 | 2969 | |
74 | [연세대 의료법윤리학연구원] 제1차 ‘국민 참여 보건연구자원 개발사업-정… | admin | 2017.11.30 | 3907 | |
73 | [질병관리본부] 국립중앙인체자원은행 분양수수료 납부제 도입 사전안내 및 … | admin | 2017.11.02 | 4058 | |
72 | [질병관리본부]"제3회 바이오뱅크 포럼" 개최 | admin | 2017.10.27 | 2881 | |
71 | [KBSI]5th INTERNATIONAL CONFERENCE on An… | admin | 2017.10.12 | 2322 | |
70 | 5th KSEV(한국 세포밖 소포체 학회) Annual Meeting(1… | admin | 2017.09.20 | 644 | |
69 | KBSI 신규이용자를 위한 질량분석 아카데미 개최안내(17/10/16-1… | admin | 2017.09.12 | 4148 | |
68 | HPP Workshop plans & C-HPP program in Du… | admin | 2017.08.21 | 2697 | |
67 | ClinProt2017 conference in Moscow, Oct 3… | admin | 2017.08.14 | 2090 | |
66 | 2017년도 한국분자세포생물학회 정기학술대회(9.12-14, 코엑스) | admin | 2017.06.21 | 2201 | |
65 | [KMPC] AMMRA-Mouse Workshop(8.28-29,NEST… | admin | 2017.05.18 | 2195 | |
64 | 한국분자세포생물학회 제13회 경암바이오유스캠프(7.26, 연세대) | admin | 2017.05.18 | 2676 |
한국단백체학회
부산광역시 부산진구 진사로83번길 81, 1층(개금동, 미래의생명센터)
대표: 한진 / 고유번호 110-82-61066
Tel. 02-393-8328 / E-mail. admin@khupo.org
한국단백체학회(KHUPO) 사무국
공식 사무국: ㈜더플랜비
부산광역시 해운대구 우동 APEC로 55 벡스코 제 1전시장 B10호
Tel. 070-7587-0115 E-mail: theplanb@planbgroup.org
Homepage : https://www.planbgroup.org/
COPYRIGHT ⓒ 2015 KHUPO 한국단백체학회